Albuquerque, New Mexico’s largest city, sits in the high desert. Its modern Downtown core contrasts with Old Town Albuquerque, dating to the city’s 1706 founding as a Spanish colony. Old Town is filled with historic adobe buildings, such as San Felipe de Neri Church, 5 museums, and shops selling Native American handicrafts. Nearby, The Indian Pueblo Cultural Center traces the area’s tribal history.

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Metro population: 915,927